
Revolution pet medicine is a topical treatment that kills fleas, ticks, and chewing lice, and also treats sarcoptic mange and ear mites.
It's a convenient and easy-to-use solution that can be applied directly to your pet's skin, providing quick relief from these pesky parasites.
What Is Selamectin?
Selamectin is a safe and simple monthly topical medication used to protect your dog or cat from heartworms, fleas, and ear mites.
Revolution, the brand name for Selamectin, requires a prescription from your veterinarian to use.
Selamectin is used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange.
A 3-pack of Revolution, which lasts 3 months, contains 3 doses of Selamectin.
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Benefits and How It Works
Revolution pet medicine is a game-changer for pet owners. It protects your pet from heartworms and fleas.
One of the main benefits of Revolution is that it's safe and easy to use. You only need to administer it once a month.
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Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease.
Here are some of the specific benefits of Revolution:
- Protects your pet from heartworms and fleas
- Fights both internal and surface parasitic infections
- Treats Sarcoptic mange in dogs
- Treats and controls ear mites
- Controls American Dog Tick infestation
- Treats and controls roundworms and hookworms in cats
- Only administered once a month
- Safe and easy to use
Revolution is also effective against ear mites, roundworm, and hookworm infections in cats. This is especially important for kittens, who are more susceptible to these parasites.
Revolution is available for cats and kittens 8 weeks of age and older, and dogs and puppies 6 weeks of age and older.
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Precautions and Cautions
Don't use Revolution on sick, weak, or underweight animals, as it can be ineffective and even cause harm. This is especially true for cats and dogs under a certain age: 8 weeks for cats and 6 weeks for dogs.
It's also crucial to test your dog for heartworms before using Revolution. This is a simple step that can prevent potential complications.
In cats, Revolution may cause side effects like digestive upset, temporary hair loss, and inflammation at the application site. For people, Revolution can be irritating to skin and eyes, so be sure to wash your hands thoroughly after use.
To avoid reinfection, daily cleanup of stools is recommended, especially if your pet has hookworms. You should also eliminate fleas from your pet and household, and avoid feeding your pet rodents or uncooked meat or fish.
Cautions
If you're considering using Revolution on your pet, it's essential to be aware of the cautions. Do not use Revolution on sick, weak, or underweight animals. Use only on cats 8 weeks and older. Use only on dogs 6 weeks and older.
Prior to administration, dogs should be tested for heartworms. In cats, side effects may include digestive upset and temporary hair loss at application site with possible inflammation. In people, Revolution may be irritating to skin and eyes. Wash hands after use.
Here are some specific cautions to keep in mind:
It's also crucial to maintain good personal hygiene to prevent the transmission of hookworms to humans. Eliminate fleas on your pet and in the household, and avoid feeding your pet rodents or uncooked meat or fish.
Possible Side Effects
Side effects from Revolution products are uncommon, but may include irritation or hair loss at the application site.
Temporary hair loss at the application site is the most common side effect, affecting about 1% of cats.
In addition to hair loss, cats may experience digestive upset, poor appetite, drooling, an abnormally increased breathing rate, and muscle tremors.
In rare cases, cats may experience more severe side effects such as seizures or collapse.
Dogs may experience seizures as well, but it's less common.
Some cats may also experience conjunctivitis, sneezing, fever, generalized itching, hives, or lack of coordination.
If your cat licks the product off after application, they may experience excessive drooling, agitation, and vomiting due to the bitter taste.
To avoid this, apply the product to the skin in front of the shoulder blades at the back of the neck, a location even the most flexible cat cannot reach to lick.
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In multiple cat households, separating housemates for up to 24 hours after application may be advisable to allow the product to fully dry.
Here's a list of possible side effects in cats and dogs:
- Irritation or hair loss at the application site
- Vomiting
- Diarrhea
- Loss of appetite
- Lethargy
- Drooling
- Increased breathing rate
- Tremors
- Conjunctivitis (in cats)
- Sneezing (in cats)
- Fever
- Generalized itching
- Hives
- Lack of coordination
- Seizures (in dogs)
Considerations
If you're considering using Revolution on your pet, there are some important considerations to keep in mind.
Revolution should not be used on sick, weak, or underweight animals. This is crucial to ensure the health and safety of your pet.
In cats, Revolution has been tested and is considered safe in pregnant and lactating female cats and dogs, as well as breeding male and female cats and dogs. However, it's still essential to consult with your veterinarian before using Revolution on your pet.
In cats with a history of neurological disorders, Revolution should be used with caution. This is because some cats may be more sensitive to the medication.
If your pet has ever had an allergic reaction to Revolution, you should discuss this with your veterinarian before applying the medication.
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It's also essential to note that Revolution should not be used on dogs that have not been tested for heartworms prior to administration.
To prevent reinfection, daily cleanup of stools is recommended, especially if you have rodents or uncooked meat or fish in your home.
Here are some key considerations to keep in mind when using Revolution on your pet:
Remember to always consult with your veterinarian before using Revolution on your pet.
Dosage and Application
Revolution products need to be applied every 30 days for the best protection.
You should always follow the instructions on the packaging, which is the best way to ensure you're using the product correctly.
To apply Revolution, first push down the cap on the vial to puncture it, then remove the cap and apply the entire contents to the skin along the back of the neck in front of the shoulders.
This spot is ideal because your kitty can't reach it to lick the product off.
Revolution products are waterproof within 2 hours of application, but it's still recommended to wait 24 hours before bathing your kitty.
Bathing too close to application time can reduce the product's effectiveness.
If you're unsure if the product was applied correctly or if all of it was used, it's usually safest to wait until the next application time rather than applying an additional dose.
Missed Dose and Overdose
If you forget to give a dose of Revolution, give it as soon as you remember. However, if your veterinarian has directed you to give this medication on a different dosing schedule, contact them for further instructions.
A missed dose of Revolution should be given on the same day it was missed, but do not give extra or double doses. If your pet has a history of taking Revolution, you may want to set reminders to ensure you don't miss a dose.
In case of an overdose, contact your veterinarian, seek emergency veterinary care, or call an animal poison control center. Oral overdoses can cause symptoms such as loss of appetite, tremors, lethargy, drooling, vomiting, and diarrhea in cats.
If you suspect an overdose or used the wrong product on your pet, immediately contact your veterinarian or an animal poison control center. The ASPCA Animal Poison Control can be reached at 888-426-4435, and Pet Poison Helpline is available at 855-764-7661.
Missed a Dose?
If you forget to give a dose of Revolution or Revolution Plus, don't panic. Give it when you remember, as long as it's not more than 30 days since the last dose. If your veterinarian has directed you to give it on a different schedule, contact them for further instructions.
The key is to follow the original schedule as closely as possible. Don't give extra or double doses, as this can be counterproductive. Always consult your veterinarian if you're unsure about the dosing schedule.
If you're using Revolution or Revolution Plus, it's essential to follow the instructions on the packaging. The product is typically applied once a month, every 30 days, for optimal protection. Always apply the entire contents of the vial to the skin along the back of the neck in front of the shoulders.
If you're unsure whether the product was administered correctly or if all of it was applied, it's usually safest not to apply an additional dose. If you have any questions or concerns, contact your veterinarian for guidance.
Here's a quick summary of what to do if you miss a dose:
Selamectin Overdose in Pets
If you suspect an overdose of Selamectin in your pet, it's essential to know what to do. Contact your veterinarian or seek emergency veterinary care immediately.
Symptoms of overdose can vary depending on the method of administration. For topical overdoses, you might not notice any additional symptoms beyond the usual side effects. However, oral overdoses can cause more severe symptoms, including loss of appetite, tremors, lethargy, drooling, vomiting, and diarrhea in cats.
If you accidentally give the topical product by mouth, or if you suspect an overdose, contact your veterinarian or seek emergency veterinary care right away. Consultation fees may apply, but it's crucial to get your pet the help they need as soon as possible.
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Here are some resources to contact in case of an overdose:
- Pet Poison Helpline: 855-764-7661
- ASPCA Animal Poison Control: 888-426-4435
Keep in mind that while rare, overdose symptoms can include salivation and lack of coordination, as well as the side effects listed above. If you're ever in doubt, it's always best to err on the side of caution and seek veterinary advice.
Storage and Handling
Storing Revolution pet medicine is crucial to maintain its effectiveness. Always confirm storage requirements by reading the label.
To ensure the product remains potent, store Revolution products at controlled temperatures below 86 F (30 C). This is a critical factor in maintaining the medication's quality.
Store Revolution products away from heat or open flames to prevent damage. I've seen some pet owners store their medication in a cabinet near the stove, which is not a good idea.
The provided container is designed to protect the medication from moisture and light. Keep the container closed until you're ready to administer the medication.
Keep Revolution products out of reach of children and pets to avoid any accidents or misuse. This is a common sense precaution that can prevent a lot of trouble.
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Cat and Weight-Specific Information
When it comes to giving Revolution pet medicine to your cat, there are a few things to keep in mind. You should not use Revolution on kittens under 8 weeks of age.
It's also worth noting that Revolution is safe for use on pregnant or lactating cats. This can give you peace of mind when administering the medication to your furry friend.
Cat (Blue)
The Cat (Blue) section of the Revolution product is specifically designed for cats.
Revolution Cat (Blue) contains 60mg/mL Selamectin as its active constituent.
The product is available in various vial sizes: 6, 12, and 24.
The expiry date for these vials is January 2027.
Revolution Cat (Blue) treats cats, with a specific age range mentioned in the product literature, but it's not specified in the provided information.
This product has the same active constituents as brand-name Revolution and Sel..
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Selapro for 5.1-10kg
Selapro for cats weighing 2.6-7.5kg is available, containing 60mg/mL of Selamectin.

The expiry date for this product is January 2027.
For cats of this weight, Selapro is specifically formulated to meet their needs.
You can purchase Selapro for this weight range, with prices varying depending on the retailer.
Selapro for dogs weighing 5.1-10kg is also available, containing 120mg/mL of Selamectin.
This product has an expiry date of November 2026.
Selapro for dogs of this weight range is suitable for pets weighing between 11-22lbs.
There is a cheaper option for Selapro for dogs of this weight range, priced at AU$61.90.
General Information
Revolution pet medicine is a prescription medication applied topically once a month. It's essential to use it as directed to ensure the best results.
You should not use Revolution on puppies under 6 weeks of age or kittens under 8 weeks of age. This is crucial for their safety and well-being.
Revolution is safe for use on pregnant or lactating dogs and cats, according to the product literature. This is a significant advantage for pet owners who need to protect their pets during these critical periods.
Overview
Revolution for cats is a prescription medication applied topically once a month. It's available for use on pregnant or lactating cats, making it a convenient option for pet owners with multiple pets.
Revolution for cats is safe for use on kittens over 8 weeks of age. This is a crucial consideration for pet owners who need to protect their young kittens from parasites.
It's essential to follow the product literature and apply Revolution for cats as directed to ensure its effectiveness. This means applying it topically once a month, without missing a dose.
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Ingredients:
The active ingredient in Revolution, Selamectin, is present in varying amounts depending on the pet's weight.
For puppies and kittens up to 5 lbs, each dose contains 15 mg of Selamectin.
Cats weighing between 5.1 and 15 lbs require a dose with 45 mg of Selamectin.
Dogs in the 5.1-10 lb range need a dose with 30 mg of Selamectin.

Cats between 15.1 and 22 lbs require a dose with 60 mg of Selamectin.
Dogs between 10.1 and 20 lbs also need a dose with 60 mg of Selamectin.
For dogs weighing 20.1-40 lbs, a dose with 120 mg of Selamectin is required.
Dogs in the 40.1-85 lb range need a dose with 240 mg of Selamectin.
Lastly, dogs weighing 85.1-130 lbs require a dose with 360 mg of Selamectin.
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Veterinary Guidance
When using Revolution pet medicine, it's essential to follow some guidelines to ensure your pet's health and safety.
First and foremost, maintain good personal hygiene to avoid contracting hookworms from your pet. This means washing your hands thoroughly after applying the medicine.
Eliminate fleas on your pet and in the household to prevent any potential health issues. You should also avoid feeding your pet rodents or uncooked meat or fish.
Daily cleanup of stools is crucial to prevent reinfection. This will help keep your pet and your home clean and healthy.
Don't use Revolution pet medicine on sick, weak, or underweight animals, as it may not be effective or could cause further harm.
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Core Medication Use Guidelines
To use Revolution effectively, apply it exactly as directed by your veterinarian, and if you're unsure, ask them to explain the directions to you.
Revolution is available as a unit of use applicator tube containing the specific amount of medication based on your pet's weight.
Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness of Revolution.
Revolution is available for cats and kittens 8 weeks of age and older, and dogs and puppies 6 weeks of age and older.
If you don't understand the directions, it's best to ask your pharmacist or veterinarian to explain them to you.
The entire contents of the tube should be used, and do not split the contents as the accuracy of the dose and effectiveness of the medication cannot be assured.
To prevent reinfection, daily cleanup of stools is recommended, especially since humans can contract hookworms from animals.
Do not use Revolution on sick, weak, or underweight animals, and do not apply it to wet hair.
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When to Call Your Vet
If you notice your pet's condition getting worse or not improving with treatment, it's essential to call your vet. This is a clear sign that something's not right, and your vet can help you figure out what to do next.
Severe side effects can be a major concern, and if you see any, it's crucial to reach out to your vet right away. These side effects can be serious, and your vet can advise on the best course of action.
If you suspect an overdose, don't hesitate to call your vet. Overdoses can be particularly serious in dogs with the MDR1 (ABCB1) gene defect.
If you have additional questions or concerns about the medication, your vet is always a good resource to call. They can provide you with the information you need to make informed decisions about your pet's care.
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What to Discuss with Vet Before Pet Application
Before applying any medication to your pet, it's essential to discuss a few things with your veterinarian. Tell your veterinarian if your pet has ever had an allergic reaction to the medication.
If your pet has a history of allergic reactions, your veterinarian may recommend an alternative treatment or closely monitor your pet for any adverse effects.
Your veterinarian needs to know if your pet has ever had an allergic reaction to the medication, so be sure to mention it.
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Frequently Asked Questions
Do vets recommend Revolution for dogs?
Vets recommend Revolution for dogs, especially for puppies as young as 6 weeks old and weighing under 5 pounds, due to its safety and effectiveness.
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