
Separation anxiety can be a real challenge for dog owners, causing destruction, barking, and even self-soothing behaviors like digging or chewing.
According to the American Kennel Club, approximately 23% of dogs suffer from separation anxiety.
If you're a dog owner experiencing this issue, you're not alone. Many dog owners have successfully managed their dog's separation anxiety with the right approach and medication.
In this comprehensive guide, we'll explore the most effective separation anxiety meds for dogs, as well as some practical tips to help you overcome this common problem.
What Is Separation Anxiety in Dogs?
Separation anxiety in dogs is a common issue that can cause significant distress for both dogs and their owners. Dogs that have suffered trauma have lasting effects on their mental peace and ability to adjust and thrive.
Dogs that were brought into the home when they were younger than 8 weeks of age may develop separation anxiety because their attachment formation is inappropriate when they leave their mother early.
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Genetic factors can also play a role in the development of anxiety, with some breeds being naturally more secure and independent.
Breeds that need more direction and attention from their owner, such as retrievers, bully breeds, and small-breed dogs, are typically more social and may be prone to separation anxiety.
Some herding dogs, like border collies, tend to have separation anxiety if they don't get enough exercise or have a job to do each day.
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What Are the Symptoms of
Dogs with separation anxiety exhibit a range of behaviors when left alone, including trembling, salivating, and destructive chewing. These behaviors can be a sign that your dog is suffering from separation anxiety.
Dogs may also exhibit anxious behaviors like pacing, whining, or trembling while you're gone or as you prepare to leave. This can be a sign that your dog is feeling anxious or stressed about being left alone.
Some common symptoms of separation anxiety in dogs include destructive acts, such as chewing or digging, particularly around doors or windows. This can be a sign that your dog is trying to escape or is feeling anxious about being left behind.
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Other signs of separation anxiety may include accidents in the house – urinating or defecating – and excessive salivation, drooling, or panting. These behaviors can be a sign that your dog is feeling anxious or stressed about being left alone.
Here are some common signs of separation anxiety in dogs:
- Destructive behaviors, like chewing or clawing at doors or walls
- Potty accidents, especially ones that happen only when you're away in an otherwise fully potty-trained pup
- Vocalization, such as whining and barking
- Drooling, especially when it only happens when you're gone
- Pacing, aka walking back and forth restlessly
It's worth noting that some dogs may exhibit mild symptoms of separation anxiety, such as occasional whimpering or whining, mild pacing, or slight changes in appetite. However, if your dog is exhibiting severe symptoms, such as intense vocalization or destructive behaviors, it's likely that they are suffering from separation anxiety.
Causes and Triggers
Puppies and dogs can develop separation anxiety due to various reasons, including never being left alone before, traumatic separation, and personality traits.
Some research suggests that a single traumatic event, such as a house robbery, can lead to separation anxiety. This highlights the importance of providing a stable and secure environment for your dog.
Life changes like a sudden switch in schedule, a move to a new house, or the sudden absence of a family member can also trigger separation anxiety. For example, a divorce, a death in the family, or a child leaving for college can cause dogs to become anxious when left alone.
Family changes, such as a family member moving out or adding a new addition, can also contribute to separation anxiety. Home changes, like rehoming or moving to a new home, can also cause issues.
Dogs that have suffered trauma or experienced a disruption in their environment are more prone to separation anxiety. This can include pet parents leaving for an extended period or pets changing homes several times.
Genetic factors can also play a role in the development of anxiety, with some breeds being naturally more secure and independent. For example, herding dogs like border collies may develop separation anxiety if they don't get enough exercise or have a job to do each day.
Here are some common triggers for separation anxiety:
- Family changes (e.g., family member moves out or adds a new addition)
- Home changes (e.g., rehoming or moving to a new home)
- Routine changes (e.g., pet parent starts a new job with longer hours)
- Disruption in environment (e.g., pet parent leaving for an extended period)
- Genetic factors (e.g., some breeds are naturally more anxious)
What Causes?

Separation anxiety in puppies and dogs can be caused by a single traumatic event in the owner's absence, such as a house robbery.
Never being left alone before can also contribute to separation anxiety in some puppies.
A sudden switch in schedule, like a change in work hours, can trigger separation anxiety in dogs.
A move to a new house can also lead to separation anxiety in dogs.
The sudden absence of a family member, such as a divorce or a child leaving for college, can cause separation anxiety in dogs.
A lack of daily exercise has been linked to separation anxiety in some research.
Clingy dogs may be more at risk for separation anxiety due to their personality.
Dog Triggers
Some dogs become anxious when they pick up clues that their human is preparing to leave, such as the sounds of keys or picking up a bag and putting on a jacket.
You can identify your dog's triggers by going through the motions you'd normally take when you're headed out, keeping an eye on your dog at each step.
If your dog starts to show symptoms of anxiety when you pick up your keys, for instance, you'll know that's a trigger for them.
Life changes like a sudden switch in schedule, a move to a new house, or the sudden absence of a family member can also trigger separation anxiety in dogs.
Research suggests that a lack of daily exercise can be a possible cause of separation anxiety in dogs.
Dogs that were brought into the home when they were younger than 8 weeks of age may also develop separation anxiety because their attachment formation is inappropriate when they leave their mother early.
Genetic factors can also play a role in the development of anxiety, with some breeds being naturally more secure and independent than others.
Here are some common departure cues that can trigger separation anxiety in dogs:
- Keys
- Picking up a bag
- Putting on a jacket
A death in the family or an unplanned absence can also trigger your dog's separation anxiety, making it essential to work on prevention and start treatment at the first sign.
Separate Triggers from Absence

Knowing what triggers your dog's anxiety is crucial. If your dog starts to pace and whine when you pick up your keys, for instance, that's a clear trigger.
Exposing your dog to that trigger regularly can help them become desensitized. Walk around the house holding and jingling your keys for about a minute, and repeat this session a couple of times per day.
This technique can be applied to any trigger that's causing your dog anxiety, not just your keys. It's essential to identify and address the specific triggers to help your dog feel more secure.
Here's an example of how to apply this technique to a few common triggers:
Treatment and Medication
Your veterinarian may prescribe anti-anxiety medication to help manage your dog's separation anxiety if the issue is severe.
In some cases, medication may be necessary to bring your dog's anxiety baseline down, making it easier to implement behavior modification techniques.
Medication options include amitriptyline, which is used to treat depression, and alprazolam, which is prescribed for anxiety and panic disorders. These require a prescription and are safe for most pets, though you'll need to consult with your vet.
Natural supplements like CBD or valerian might also bring relief from separation anxiety, but be sure to consult with your vet before giving your dog any over-the-counter products.
Some natural products that may help include dog-appeasing pheromone collars or diffusers and compression shirts.
Here are some calming supplements that use nutrients with soothing properties to help your pet relax:
- VetriScience’s Composure
- Nutramax’s Solliquin
- Purina’s Calming Care
These supplements can be a daily powdered probiotic that promotes calm, or calming treats that use soothing properties to help your pet relax.
Treatment Options
If your veterinarian recommends medication, it's often used in conjunction with soothing techniques. In severe cases, anti-anxiety medication may be prescribed to bring your dog's anxiety baseline down.
You can also explore natural supplements and homeopathic treatment options. Some popular choices include CBD or valerian, which may help alleviate separation anxiety in dogs. However, it's essential to consult with your vet before giving your dog any over-the-counter products, especially if they're already on prescription medications.
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Consider calming treats, such as those made by VetriScience or Nutramax, which use nutrients with soothing properties to help your pet relax. Daily powdered probiotics like Purina's Calming Care can also promote calmness.
A veterinary visit can help you determine the best course of treatment for your dog's separation anxiety. Your vet will discuss your dog's home and environment to identify potential triggers and check for any underlying health issues that may be contributing to the anxiety.
Here's a breakdown of the differences between mild and severe separation anxiety:
Consulting with a canine behaviorist or veterinarian can help you determine the best treatment approach for your dog's separation anxiety, especially if basic behavioral interventions aren't working.
Disease in Dogs
Separation anxiety is one of the most commonly diagnosed behavioral problems in our canine population.
It stems from fear of being removed from the pack, creating a feeling of vulnerability and insecurity. This fear is triggered when dogs can no longer see or hear their pet parent, who in their minds is the pack leader and the provider of a safe and viable life.
Separation anxiety affects dogs in various ways, causing them to become destructive, anxious, or even depressed when left alone.
Managing Separation Anxiety
Managing separation anxiety requires patience and understanding of your dog's triggers. If your dog starts to pace and whine when you pick up your keys, for instance, walk around the house holding and jingling your keys for about a minute.
Repeating this session a couple of times per day can help your dog become desensitized to the trigger. This is especially important during times of transition or change in routine, such as moving homes, being adopted, or family members returning to work or school.
Some common triggers include moving homes, being adopted after spending time in a shelter or foster home, family members returning to work or school after a long period of time at home, and death of a family member or other pet.
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Transition Period
A transition period can be a challenging time for pets, especially those prone to separation anxiety. Moving homes can be a significant change for pets, disrupting their routine and sense of security.
Being adopted after spending time in a shelter or foster home can also be a transition period for pets, as they adjust to a new environment and family. This can be a big change, especially for pets that have formed strong bonds with their previous caregivers.
Family members returning to work or school after a long period of time at home can also cause stress for pets. This change in routine can leave pets feeling anxious and uncertain.
Death of a family member or other pet can be a particularly difficult transition for pets, as they grieve and adjust to the loss.
Here are some common transition periods that can trigger separation anxiety:
- Moving homes
- Being adopted after spending time in a shelter or foster home
- Family members returning to work or school after a long period of time at home
- Death of a family member or other pet
Safe Zone Setup
Setting up a safe zone is crucial for dogs with anxiety. This is a happy place where your dog can relax and feel secure.
A comfortable bed is essential for your dog's safe zone. This could be a dog bed or even a human bed, as long as it's comfortable for your dog.
You'll also want to include a water bowl in the safe zone. This will ensure your dog has access to fresh water at all times.
A distracting, food-dispensing toy is a great addition to the safe zone. Fill a KONG Classic with one or two teaspoons of peanut butter to keep your dog occupied.
Use pet gates to keep your dog inside the safe zone, rather than closing the door to the room. This will help your dog feel less confined.
Here are the basics to include in your dog's safe zone:
- A comfortable bed
- A water bowl
- A distracting, food-dispensing toy, like the KONG Classic filled with one or two teaspoons of peanut butter
Remember, a safe zone is not a crate if your dog is not happy spending time there.
Slower Desensitization
Managing separation anxiety in dogs requires patience and a gentle approach. For dogs with severe anxiety, rapid progression in desensitization can be overwhelming.
It's crucial to let the dog lead, even if it means progressing at a snail's pace. This means starting with extremely short absences, such as just a few seconds, and gradually extending the duration as the dog becomes more comfortable.
If your dog begins to show signs of distress, it may be necessary to reduce the duration and progress even more slowly. This will prevent triggering a full anxiety response and allow your dog to feel safe and secure.
Common Issues and Concerns
Coming home to destruction is a common issue for many dog owners dealing with separation anxiety. It's exhausting and upsetting for both you and your dog.
Dogs with separation anxiety can get into distress, which is devastating for them. Thankfully, there are several steps you can take to deal with separation anxiety.
Some of the treatments for separation anxiety are the same as preventative measures and may already be part of your puppy's routine.
Concerns About My Dog
Coming home to destruction can be heartbreaking, especially for your dog who's in distress.
Dogs with separation anxiety can be exhausted and devastated by the experience.
It's essential to take steps to address separation anxiety, and some treatments are the same as preventative measures you may already be using.
Consider crate training as a treatment option to help your dog feel safe and secure when you're not home.
Coming home to a calm and relaxed dog is a relief, but it's also a sign that your efforts are working.
Some dogs may not respond to crate training, so it's essential to explore other treatment options, such as exercise and playtime before leaving the house.
A tired dog is a happy dog, and exercise can help reduce separation anxiety.
It's also crucial to consider your dog's individual needs and personality when choosing a treatment plan.
Some dogs may require more attention and interaction before leaving the house, while others may need more physical activity.
Every dog is different, and what works for one dog may not work for another.
By understanding your dog's unique needs and personality, you can develop a tailored treatment plan that addresses their separation anxiety.
With patience, consistency, and the right approach, you can help your dog overcome separation anxiety and enjoy a more peaceful and happy life.
Common Mistakes
Making mistakes is a natural part of the process when trying to help your dog with separation anxiety. With only good intentions in mind, many pet parents actually worsen their dog's anxiety with certain cues and household management.

Some common mistakes include giving your dog attention right before leaving the house, as this can create a strong association between your departure and the anxiety that follows. This can make it harder for your dog to adjust to your absence.
Leaving a TV or radio on to provide background noise can also be counterproductive, as it can actually make your dog more anxious and alert to potential threats. This is especially true if your dog is prone to barking or reacting to loud noises.
Giving your dog a treat or toy to calm them down before leaving can create a sense of dependence on these items, rather than addressing the underlying anxiety issue. This can make it harder for your dog to cope with your absence in the long run.
By being aware of these common mistakes, you can take steps to avoid them and create a more supportive environment for your dog.
Frequently Asked Questions
Can separation anxiety in dogs be cured?
Separation anxiety in dogs can be effectively managed with treatment and training, leading to a significant improvement in their behavior. Early diagnosis and intervention are key to achieving the best possible outcome.
What are the two FDA approved medications for separation anxiety in dogs?
The two FDA-approved medications for canine separation anxiety are fluoxetine (Reconcile) and clomipramine (Clomicalm). These medications have been specifically approved to help alleviate symptoms of separation anxiety in dogs.
Sources
- https://www.humanesociety.org/resources/separation-anxiety-dogs
- https://www.akc.org/expert-advice/training/dog-separation-anxiety/
- https://be.chewy.com/reducing-separation-anxiety-dog/
- https://www.dogwise.com/separation-anxiety-in-dogs-next-generation-treatment-protocols-and-practices/
- https://manypets.com/us/blog/separation-anxiety/
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